|
Symbol Name ID |
Rc3h1
RING CCCH (C3H) domains 1 MGI:2685397 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased T cell proliferation |
intestinal inflammation |
cecum inflammation |
colitis |
small intestinal inflammation |
ileum inflammation |
abnormal thymus development |
enlarged spleen |
increased spleen weight |
spleen hyperplasia |
abnormal B cell differentiation |
decreased immature B cell number |
abnormal T cell differentiation |
increased eosinophil cell number |
decreased B cell number |
increased B cell number |
increased T follicular helper cell number |
increased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
abnormal intraepithelial T cell number |
increased regulatory T cell number |
increased activated T cell number |
increased macrophage cell number |
abnormal effector T cell morphology |
abnormal spleen B cell follicle morphology |
increased splenocyte number |
abnormal germinal center B cell physiology |
decreased IgA level |
decreased IgG1 level |
increased IgG2b level |
decreased IgG3 level |
increased IgG level |
abnormal T follicular helper cell physiology |
increased circulating tumor necrosis factor level |
abnormal lymph node morphology |
abnormal lymph node germinal center morphology |
enlarged lymph nodes |
lymphoid hyperplasia |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
chronic liver inflammation |
granulomatous inflammation |
liver inflammation |
glomerulonephritis |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1Gt(CC0753)Wtsi/Rc3h1Gt(CC0753)Wtsi | ||||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1san/Rc3h1san | ||||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1tm1.2Mass/Rc3h1tm1.2Mass | * | |||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1san/Rc3h1+ | ||||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1tm1.2Cgv/Rc3h1san | ||||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1tm1.1Mass/Rc3h1tm1.1Mass Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1tm1.1Mass/Rc3h1tm1.1Mass Tg(Cd4-cre)1Cwi/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||||||||||||
| Rc3h1tm1.1Mass/Rc3h1tm1.1Mass Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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